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Lorazepam is used clinically for sedation of mechanically ventilated children, but has not been approved by the FDA for this indication in children. The purpose of this study, in response to the Written Request by FDA, is to determine the safety, efficacy, and dosage required for lorazepam compared with midazolam, which is approved by FDA for children for this indication.
On the third and fourth visits, patients are randomized to receive either their highest daily dose of lorazepam or placebo. Performance effects and postural sway are determined before drug administration and at 1, 2.5, and 5 hours after the drug is given.
Clinical Studies. The effectiveness of Ativan Injection in status epilepticus was established in two multi-center controlled trials in 177 patients. With rare exceptions, patients were between 18 and 65 years of age.
When searching for clinical trials on our website you will click on a Clinical Trial Information sheet like this example. Example Information Sheet. The first thing you should do is to see if the clinical trial is right for you. You can do this by quickly scanning the headings of the information sheet.
At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.
Ativan in clinical trials. Ativan has been widely used to treat anxiety in Huntington’s disease despite a lack of studies directly investigating its effect in the context of this disease. Nevertheless, Ativan is a medication that has been well-established in the short-term management of anxiety, with most studies performed in the late 20 th century.
Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices. Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
The different clinical trials carried out to in› vestigate its acute and subacute toxicity in animal and human experimentation demon- 298 H 0 I II {j( N-C&#92; I CH-OH CI ~ C=N 1 6 OXAZEPAM H 0 I I Q N-C&#92; I CH-0H CI ~ C=N 1 ere’ LORAZEPAM Volume XIV LORAZEPAM TRIAL-SANTOS AND ROMI basis or preponderant symptoms.